What is the primary route of administration for Loperamide (Imodium), Diphenoxylate (Lomotil), and Eluxadoline (Viberzi)?

Loperamide (Imodium), Diphenoxylate (Lomotil), and Eluxadoline (Viberzi) are primarily designed to treat diarrhea and act on the gastrointestinal tract. Their primary route of administration is oral, which facilitates ease of use and patient compliance.

By being administered orally, these medications are absorbed through the digestive system, allowing them to directly exert their antidiarrheal effects. This route is advantageous because it allows for convenient dosing and is clinically effective in managing symptoms of diarrhea.

In contrast, using intravenous, subcutaneous, or topical routes would not be suitable for these medications due to their intended effects on the gut. Intravenous and subcutaneous routes are typically reserved for situations requiring rapid action or when a patient cannot take medications orally, while topical administration is used for localized conditions that do not require systemic absorption. In summary, the oral route is the most effective and practical for Loperamide, Diphenoxylate, and Eluxadoline in treating diarrhea.